Rapid Screening Phenotype Test To Evaluate CYP 2C19 Enzyme Activity Using Stable Isotope [13C]Pantoprazole
Status:
Completed
Trial end date:
2009-01-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to determine the function of an enzyme that breaks down drugs
and helps the removal of drugs from your body. This enzyme is called cytochrome P450 2C19 and
is located in your liver. Exposure to other medications or variations in genes that you have
inherited from your parents, may speed up or slow the function of this enzyme. As a result,
some patients may develop unwanted effects from a drug while some other patients may not get
benefit from taking the same drug. The aim of this study is to determine the function of this
enzyme in your liver. We will do this by performing a series of breath tests and blood
samples after you take pantoprazole. Pantoprazole is approved as an oral and intravenous drug
by the Food and Drug Administration (FDA).